One-Leg workout may ease pain in both knees for seniors

NCT ID NCT07490977

Not yet recruiting Symptom relief Sponsor: University of Zagreb Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study explores whether exercising just one leg can improve strength, balance, and pain in both legs for older adults with knee osteoarthritis. Forty-five participants aged 60-80 will be assigned to different unilateral training programs for 8 weeks. Researchers will measure changes in balance, movement control, and pain to see if the benefits transfer to the untrained leg.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: unilateral strength and balance training program
What this could lead to: If it works, this could offer a simpler, less painful way to improve mobility and reduce fall risk in older adults with knee osteoarthritis.
What could go wrong: This is a small, early-stage study with only 45 participants, so results may not apply widely. The training may not produce meaningful improvements in the untrained leg.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KNEE OSTEOARTHRITIS (OA)

Contacts and locations

Locations

University of Zagreb Faculty of Kinesiology

Zagreb, 10000, Croatia

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