Scientists probe gut hormones to unlock diabetes mystery in cystic fibrosis

NCT ID NCT01851694

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to understand why many people with cystic fibrosis develop diabetes. Researchers will give two gut hormones, GLP-1 and GIP, to 45 adults with cystic fibrosis and measure how their pancreas releases insulin. The goal is to learn more about cystic fibrosis-related diabetes and find better ways to treat it in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GLP-1 and GIP (hormones that boost insulin)

What this could lead to

If successful, this research could point toward new treatment options for cystic fibrosis-related diabetes.

What could go wrong

This is an early-stage observational study with only 45 participants, so results may not apply to everyone. It aims to understand the disease, not test a treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cystic fibrosis cystic fibrosis-related diabetes diabetes mellitus exocrine pancreatic insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Philadelphia and University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19060, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••