Sound waves and clot-busters: a new hope for PE survivors?
NCT ID NCT06143969
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tracks 180 people who had a serious but stable pulmonary embolism (a blood clot in the lung) and received a treatment that uses ultrasound waves to help a clot-busting drug work better. The main goal is to see if this approach reduces the chance of developing pulmonary hypertension (high blood pressure in the lungs) within six months. Researchers will also check heart function and other outcomes over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ultrasound-assisted, catheter-directed thrombolysis (procedure using EkoSonic system and alteplase)
What this could lead to
If successful, this could show that the procedure lowers the risk of developing pulmonary hypertension after a blood clot in the lungs.
What could go wrong
This is an observational study, not a randomized trial, so results may be less definitive. The procedure itself carries risks like bleeding or vessel damage.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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ASST GOM Niguarda
RECRUITINGMilan, Italia, 20162, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••