Can a simple ultrasound spot hidden liver danger in immune disorder patients?

NCT ID NCT06145100

Completed Knowledge-focused Sponsor: University Hospital Freiburg Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether ultrasound and stiffness measurements of the liver and spleen can predict a serious condition called portal hypertension in people with common variable immunodeficiency (CVID). Researchers examined 250 CVID patients during routine visits, using non-invasive imaging and blood samples. The goal was to find better ways to detect liver complications without needing more invasive tests.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a non-invasive way to detect serious liver complications in CVID patients, reducing the need for invasive procedures.
What could go wrong: This is an observational study, not a treatment trial. The results may not change current care and could be limited by the specific patient group studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

common variable immunodeficiency nodular regenerative hyperplasia of the liver

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COMMON VARIABLE IMMUNODEFICIENCY NON-CIRRHOTIC PORTAL HYPERTENSION

Contacts and locations

Locations

University Medical Center Freiburg, Department of Medicine II

Freiburg im Breisgau, 79106, Germany

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