Can umbilical cord stem cells help repair spinal cord injuries?

NCT ID NCT07739043

First seen Jul 31, 2026 ยท Last updated Jul 31, 2026

Summary

This trial is testing whether a single injection of stem cells from umbilical cord tissue, given into the spinal fluid, is safe and tolerable for people who have had a traumatic spinal cord injury within the past ten years. The study will monitor participants for side effects and check for any significant improvements in function over the following year. It is an early-stage study involving a small number of participants.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Allogeneic umbilical cord-derived mesenchymal stem cells (UC-MSC), given as a single injection into the spinal fluid
What this could lead to
If safe and effective, this approach could offer a new way to improve nerve function and quality of life for people living with spinal cord injury.
What could go wrong
This is a very early, small study focused on safety, so it may not show clear benefit. There are also risks from the injection procedure itself, such as infection or nerve damage.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The University of Chicago

    Chicago, Illinois, 60637, United States

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Other studies related to the condition(s) this trial covers.