Could extra doses of a common drug speed up recovery after joint replacement?

NCT ID NCT06208267

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether giving extra doses of tranexamic acid (TXA) after hip or knee replacement surgery can reduce bleeding, pain, and help people move around sooner. TXA is a drug already used during surgery to prevent blood loss. The trial will compare the standard single dose to additional oral doses given over 24 hours. About 210 adults having hip or knee replacement at one hospital in Canada will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
tranexamic acid
What this could lead to
If it works, this could lead to a simple, low-cost way to help people recover faster and with less pain after hip or knee replacement surgery.
What could go wrong
This is a small, early-stage trial testing different dosing schedules. The benefits may be modest, and there is a small risk of side effects like allergic reactions or blood clots.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St. Mary's Hospital Center

    RECRUITING

    Montreal, Quebec, H3T 1M5, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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