Could extra doses of a common drug speed up recovery after joint replacement?
NCT ID NCT06208267
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether giving extra doses of tranexamic acid (TXA) after hip or knee replacement surgery can reduce bleeding, pain, and help people move around sooner. TXA is a drug already used during surgery to prevent blood loss. The trial will compare the standard single dose to additional oral doses given over 24 hours. About 210 adults having hip or knee replacement at one hospital in Canada will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- tranexamic acid
- What this could lead to
- If it works, this could lead to a simple, low-cost way to help people recover faster and with less pain after hip or knee replacement surgery.
- What could go wrong
- This is a small, early-stage trial testing different dosing schedules. The benefits may be modest, and there is a small risk of side effects like allergic reactions or blood clots.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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St. Mary's Hospital Center
RECRUITINGMontreal, Quebec, H3T 1M5, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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