Glow-in-the-Dark dye could help surgeons spot hidden brain tumors
NCT ID NCT03262636
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed Phase 1 trial tested whether a dye called indocyanine green (ICG) can make brain tumor cells glow during surgery, helping surgeons see and remove them more completely. 363 adults with brain tumors received an ICG injection before surgery, and special cameras captured the glow. The goal was to improve how much tumor is removed, which could lower the chance of the tumor coming back and improve survival.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
indocyanine green (ICG)
What this could lead to
If successful, this imaging technique could help surgeons remove more tumor tissue during brain surgery, potentially improving survival and reducing recurrence.
What could go wrong
This is an early-phase trial focused on safety and imaging accuracy, not yet proven to improve survival. The dye may not highlight all tumor cells, and results may not apply to all brain tumor types.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.