Mapping the Brain's hidden damage after radiation in kids
NCT ID NCT06185686
First seen Jul 17, 2026 · Last updated Jul 17, 2026
Summary
This study looks at how radiation therapy changes the brain's resting state networks in children and teens (ages 8-21) with newly diagnosed brain tumors. Participants will have MRI scans and cognitive tests before and about a year after proton radiation. The goal is to understand why some children experience thinking and memory problems after treatment, which could lead to better ways to protect the brain.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- radiation therapy (proton radiation) and MRI scans
- What this could lead to
- If successful, this could help predict which children are at risk for cognitive decline after radiation, guiding future treatments to protect brain function.
- What could go wrong
- This is a small, early-stage observational study with only 16 participants, so results may not apply to all children. It measures brain changes but does not test a new treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Washington University School of Medicine/Saint Louis Children's Hospital
RECRUITINGSt Louis, Missouri, 63110, United States
Contact
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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