Mouthwash may stop cancer Drug's painful side effect

NCT ID NCT07357597

Recruiting now Symptom relief Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 06, 2026 · Updated 3 times

Summary

This study tests if a steroid mouthwash can prevent or reduce mouth sores caused by the cancer drug datopotamab deruxtecan (Dato-DXd). About 100 adults with advanced breast or lung cancer will use the mouthwash and be monitored for 12 weeks. The goal is to see if this simple step can improve quality of life during treatment.

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Conditions

The condition(s) this trial relates to.

breast cancer hormone receptor-positive breast cancer non-small cell lung carcinoma triple-negative breast carcinoma stomatitis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STOMATITIS

Contacts and locations

Locations

Research Site
WITHDRAWN

Tucson, Arizona, 85719, United States
Research Site
RECRUITING

Hot Springs, Arkansas, 71913, United States
Research Site
RECRUITING

Little Rock, Arkansas, 72205, United States
Research Site
NOT_YET_RECRUITING

Duarte, California, 91010, United States
Research Site
RECRUITING

Glendale, California, 91204, United States
Research Site
RECRUITING

Lakewood, California, 90805, United States
Research Site
RECRUITING

Long Beach, California, 90806, United States
Research Site
NOT_YET_RECRUITING

Torrance, California, 90505, United States
Research Site
WITHDRAWN

Washington D.C., District of Columbia, 20037, United States
Research Site
NOT_YET_RECRUITING

Plantation, Florida, 33322, United States
Research Site
RECRUITING

Athens, Georgia, 30607, United States
Research Site
WITHDRAWN

Boise, Idaho, 83706, United States
Research Site
WITHDRAWN

Park Ridge, Illinois, 60068, United States
Research Site
RECRUITING

Fort Wayne, Indiana, 46825, United States
Research Site
NOT_YET_RECRUITING

Elizabethtown, Kentucky, 42701, United States
Research Site
NOT_YET_RECRUITING

Lexington, Kentucky, 40503, United States
Research Site
NOT_YET_RECRUITING

Lexington, Kentucky, 40509, United States
Research Site
NOT_YET_RECRUITING

Louisville, Kentucky, 40207, United States
Research Site
NOT_YET_RECRUITING

New Orleans, Louisiana, 70112, United States
Research Site
WITHDRAWN

Frederick, Maryland, 21702, United States
Research Site
NOT_YET_RECRUITING

Glenn Dale, Maryland, 20769, United States
Research Site
NOT_YET_RECRUITING

Detroit, Michigan, 48202, United States
Research Site
NOT_YET_RECRUITING

Grayling, Michigan, 49738, United States
Research Site
RECRUITING

Minneapolis, Minnesota, 55426, United States
Research Site
NOT_YET_RECRUITING

Kansas City, Missouri, 64111, United States
Research Site
WITHDRAWN

Reno, Nevada, 89502, United States
Research Site
WITHDRAWN

Lebanon, New Hampshire, 03756, United States
Research Site
RECRUITING

East Syracuse, New York, 13057, United States
Research Site
NOT_YET_RECRUITING

Westbury, New York, 11590, United States
Research Site
WITHDRAWN

White Plains, New York, 10601, United States
Research Site
NOT_YET_RECRUITING

Greensboro, North Carolina, 27403, United States
Research Site
RECRUITING

Wilson, North Carolina, 27893, United States
Research Site
NOT_YET_RECRUITING

Cleveland, Ohio, 44106, United States
Research Site
RECRUITING

Wynnewood, Pennsylvania, 19096, United States
Research Site
NOT_YET_RECRUITING

Knoxville, Tennessee, 37920, United States
Research Site
NOT_YET_RECRUITING

Fairfax, Virginia, 22031, United States
Research Site
WITHDRAWN

Charleston, West Virginia, 25304, United States
Research Site
NOT_YET_RECRUITING

Morgantown, West Virginia, 26506, United States
Research Site
NOT_YET_RECRUITING

Waukesha, Wisconsin, 53188, United States

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