New drug combo shows promise for tough cancers

NCT ID NCT05489211

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Apr 09, 2026 · Last updated May 13, 2026 · Updated 7 times

Summary

This study tests a new drug called datopotamab deruxtecan (Dato-DXd) alone or with other cancer drugs in people with advanced solid tumors that have spread. The goal is to see if the drug can shrink tumors or slow cancer growth. About 454 adults with cancers like endometrial, gastric, prostate, ovarian, colorectal, urothelial, or biliary tract cancer will take part. The study is currently recruiting.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Research Site
RECRUITING

Los Angeles, California, 90095, United States
Research Site
WITHDRAWN

San Diego, California, 92103, United States
Research Site
RECRUITING

Santa Rosa, California, 95403, United States
Research Site
WITHDRAWN

Muncie, Indiana, 47303, United States
Research Site
WITHDRAWN

Kansas City, Kansas, 66160, United States
Research Site
WITHDRAWN

Boston, Massachusetts, 02114, United States
Research Site
COMPLETED

Boston, Massachusetts, 02215, United States
Research Site
RECRUITING

Grand Rapids, Michigan, 49503, United States
Research Site
RECRUITING

East Brunswick, New Jersey, 08816, United States
Research Site
RECRUITING

Albuquerque, New Mexico, 87109, United States
Research Site
RECRUITING

Commack, New York, 11725, United States
Research Site
RECRUITING

Cincinnati, Ohio, 45219, United States
Research Site
RECRUITING

Columbus, Ohio, 43219, United States
Research Site
WITHDRAWN

Portland, Oregon, 97239, United States
Research Site
RECRUITING

Nashville, Tennessee, 37203, United States
Research Site
WITHDRAWN

Nashville, Tennessee, 37232, United States
Research Site
RECRUITING

Houston, Texas, 77030, United States
Research Site
RECRUITING

Madison, Wisconsin, 53792, United States
Research Site
WITHDRAWN

Toronto, Ontario, M4N 3M5, Canada
Research Site
RECRUITING

Toronto, Ontario, M5G 2M9, Canada
Research Site
WITHDRAWN

Montreal, Quebec, H2X 0A9, Canada
Research Site
RECRUITING

Montreal, Quebec, H4A 3J1, Canada
Research Site
RECRUITING

Québec, Quebec, G1J 1Z4, Canada
Research Site
WITHDRAWN

Changsha, 410013, China
Research Site
WITHDRAWN

Chongqing, 400030, China
Research Site
RECRUITING

Guangzhou, 510060, China
Research Site
WITHDRAWN

Guangzhou, 510120, China
Research Site
RECRUITING

Hangzhou, 310020, China
Research Site
WITHDRAWN

Hefei, 230001, China
Research Site
RECRUITING

Shanghai, 200032, China
Research Site
NOT_YET_RECRUITING

Shanghai, 200032, China
Research Site
WITHDRAWN

Shenyang, 110016, China
Research Site
WITHDRAWN

Wuhan, 430030, China
Research Site
WITHDRAWN

Wuhan, 430079, China
Research Site
WITHDRAWN

Xi'an, 710000, China
Research Site
RECRUITING

Zhengzhou, 450052, China
Research Site
RECRUITING

Bordeaux, 33076, France
Research Site
RECRUITING

Lyon, 69373, France
Research Site
WITHDRAWN

Marseille, 13273, France
Research Site
RECRUITING

Suresnes, 92150, France
Research Site
WITHDRAWN

Berlin, 10117, Germany
Research Site
WITHDRAWN

Essen, 45136, Germany
Research Site
WITHDRAWN

Hanover, 30625, Germany
Research Site
WITHDRAWN

München, 81377, Germany
Research Site
WITHDRAWN

Regensburg, 93053, Germany
Research Site
WITHDRAWN

Florence, 50139, Italy
Research Site
WITHDRAWN

Genova, 16132, Italy
Research Site
RECRUITING

Milan, 20132, Italy
Research Site
WITHDRAWN

Milan, 20141, Italy
Research Site
RECRUITING

Milan, 20162, Italy
Research Site
RECRUITING

Naples, 80131, Italy
Research Site
WITHDRAWN

Rome, 00168, Italy
Research Site
RECRUITING

Chūōku, 104-0045, Japan
Research Site
RECRUITING

Kashiwa, 277-8577, Japan
Research Site
RECRUITING

Kōtoku, 135-8550, Japan
Research Site
RECRUITING

Nagoya, 464-8681, Japan
Research Site
RECRUITING

Shinagawa-ku, 142-8666, Japan
Research Site
RECRUITING

Suita-shi, 565-0871, Japan
Research Site
RECRUITING

Gliwice, 44-102, Poland
Research Site
RECRUITING

Krakow, 31-501, Poland
Research Site
WITHDRAWN

Lodz, 92-213, Poland
Research Site
WITHDRAWN

Poznan, 61-866, Poland
Research Site
RECRUITING

Warsaw, 02-781, Poland
Research Site
RECRUITING

Seoul, 03722, South Korea
Research Site
RECRUITING

Seoul, 05505, South Korea
Research Site
RECRUITING

Seoul, 06351, South Korea
Research Site
RECRUITING

Seoul, 110-744, South Korea
Research Site
RECRUITING

Barcelona, 8035, Spain
Research Site
TERMINATED

Córdoba, 14004, Spain
Research Site
RECRUITING

Madrid, 28046, Spain
Research Site
RECRUITING

Málaga, 29010, Spain
Research Site
RECRUITING

Pamplona, 31008, Spain
Research Site
RECRUITING

Seville, 41013, Spain
Research Site
WITHDRAWN

Basel, 4031, Switzerland
Research Site
WITHDRAWN

Bellinzona, 6500, Switzerland
Research Site
WITHDRAWN

Sankt Gallen, 9007, Switzerland
Research Site
RECRUITING

Liou Ying Township, 736, Taiwan
Research Site
RECRUITING

Taipei, 100, Taiwan
Research Site
RECRUITING

Taipei, 11259, Taiwan
Research Site
RECRUITING

Taipei, 112, Taiwan
Research Site
RECRUITING

Taoyuan, 333, Taiwan
Research Site
RECRUITING

Ankara, 06620, Turkey (Türkiye)
Research Site
RECRUITING

Ankara, 06800, Turkey (Türkiye)
Research Site
RECRUITING

Cordaleo, 35575, Turkey (Türkiye)
Research Site
RECRUITING

Edirne, 22030, Turkey (Türkiye)
Research Site
RECRUITING

Kadıkoy/Istanbul, 34722, Turkey (Türkiye)
Research Site
RECRUITING

Konya, 42080, Turkey (Türkiye)
Research Site
RECRUITING

Pamukkale, 20070, Turkey (Türkiye)
Research Site
WITHDRAWN

Samsun, 55139, Turkey (Türkiye)
Research Site
RECRUITING

Cambridge, CB2 0QQ, United Kingdom
Research Site
RECRUITING

Dundee, DD1 9SY, United Kingdom
Research Site
RECRUITING

London, EC1A 7BE, United Kingdom
Research Site
RECRUITING

London, NW1 2PG, United Kingdom
Research Site
RECRUITING

London, SE1 9RT, United Kingdom
Research Site
RECRUITING

Manchester, M20 4BX, United Kingdom

Conditions

Explore the condition pages connected to this study.

BILIARY TRACT CANCER COLORECTAL CANCER ENDOMETRIAL CANCER ENDOMETRIAL CANCER GASTRIC CANCER METASTATIC CASTRATION-RESISTANT PROSTATE CANCER OVARIAN CANCER UROTHELIAL CANCER