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Can a bone scan replace MRI for arthritis detection?

NCT ID NCT07784257

Diagnosis Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 25, 2026 · Last updated Sep 03, 2026 · Updated 3 times

Summary

This study investigates whether triphasic bone scans combined with SPECT/CT can accurately diagnose osteoarthritis in the foot and ankle, using MRI as the gold standard. Researchers will compare the imaging results from 40 adults with chronic foot or ankle pain to see how well the bone scans identify affected joints. If successful, this could provide a valuable diagnostic tool for patients who cannot undergo MRI.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Triphasic bone scintigraphy and SPECT/CT imaging
What this could lead to
If these imaging methods prove accurate, they could offer a reliable, possibly more accessible alternative to MRI for diagnosing foot and ankle osteoarthritis.
What could go wrong
This is a small, early-stage diagnostic study, so results may not apply broadly. The accuracy of these scans could vary and might not match MRI's detail.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Jan 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients with chronic foot and/or ankle pain suspected of osteoarthritis referred to the Nuclear Medicine Unit at Assiut University Hospital who meet the eligibility criteria.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Age ≥ 18 years * Patients presenting with chronic foot and/or ankle pain suspected to be due to osteoarthritis * Clinical and/or radiographic suspicion of foot or ankle osteoarthritis Exclusion Criteria: * Age \< 18 years * Previous surgery or joint replacement of the affected foot or ankle * Bone tumors or metastatic bone disease * Active osteomyelitis or septic arthritis * Inflammatory arthropathies (e.g., rheumatoid arthritis, psoriatic arthritis, gout)

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Conditions

The condition(s) this trial relates to.

arthropathy osteoarthritis osteoarthritis, toe

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ankle osteoarthritis Foot osteoarthritis Joint diseases Osteoarthritis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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