New hope for aggressive brain tumors? triple drug combo under trial
NCT ID NCT07263438
First seen Dec 16, 2025 · Last updated Apr 28, 2026 · Updated 19 times
Summary
This study tests whether combining three drugs (trimipramine, atezolizumab, and bevacizumab) can help people with recurrent glioblastoma, a fast-growing brain cancer that has returned after standard treatment. About 59 participants will receive the drug combination for up to 2 years. The goal is to see if the treatment slows tumor growth and to measure how much trimipramine reaches the tumor tissue.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Bern Inselspital
RECRUITINGBern, Canton of Bern, 3010, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Centre Hospitalier Universitaire Vaudois
RECRUITINGLausanne, Canton of Vaud, 1011, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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HFR Fribourg - Hôpital cantonal
RECRUITINGFribourg, Canton of Fribourg, 1708, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Kantonsspital Aarau
RECRUITINGAarau, Canton of Aargau, 5001, Switzerland
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Luzerner Kantonsspital
RECRUITINGLucerne, Canton of Lucerne, 6000, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Universitätsspital Basel
RECRUITINGBasel, Basel, 4031, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Universitätsspital Zürich
RECRUITINGZurich, Canton of Zurich, 8091, Switzerland
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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