Centre Hospitalier Universitaire Vaudois

This early-phase trial is testing a new treatment called LauT-1 for people with advanced melanoma or sarcoma that has not responded to standard therapies. LauT-1 is made by taking a patient's own immune cells, modifying them in a lab to better recognize and attack their cancer, a…

This study is testing a procedure called autologous chondrocyte implantation (ACI) for people with knee cartilage defects. Doctors take a sample of the patient's own cartilage cells, grow them in a lab, and then implant them into the damaged area. The goal is to see if this appro…

This study tests whether a high-dose, high-intensity neurorehabilitation program using digital devices (MindMotion GO, Izar) is feasible for stroke patients. 120 adults with stroke will train about one hour per day, five days a week, across inpatient and home settings. The goal i…

This phase II trial tests a combination of three drugs—trimipramine (an antidepressant), atezolizumab (an immunotherapy), and bevacizumab (a drug that cuts off blood supply to tumors)—in 59 patients whose glioblastoma has returned after standard treatment. The goal is to see if t…

This study tests whether giving patients a special nutritional drink (immunonutrition) before bladder removal surgery can reduce complications like infections. About 232 adults having open cystectomy for various bladder conditions will be randomly assigned to receive the drink or…

This study explores whether a smartphone can reliably screen for high blood pressure by analyzing video recorded at your fingertip. About 100 adults will record their blood pressure using both a smartphone and a standard arm cuff, three times each morning and evening for a week. …

This study tests whether using ultrasound to guide a numbing injection for circumcision works better than the standard method based on feel. About 216 boys under 18 will be randomly assigned to one of two groups. The goal is to see if ultrasound reduces the need for strong painki…

This study aims to create a portable, radiation-free software that uses facial recognition and neck movement analysis to predict how difficult it will be to place a breathing tube during anesthesia. Researchers will enroll 1800 adults undergoing planned surgery to test the softwa…