Blood test could spare kidney patients painful biopsies

NCT ID NCT04239703

Recruiting now Diagnosis Sponsor: University of Alberta Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a blood test (called DD-cfDNA) can accurately detect kidney transplant rejection, potentially replacing the need for invasive kidney biopsies. Researchers will compare the blood test results with standard biopsy analysis in 300 kidney transplant recipients. If successful, this could make monitoring for rejection safer and more comfortable for patients.

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Conditions

The condition(s) this trial relates to.

transplant rejection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KIDNEY TRANSPLANT REJECTION

Contacts and locations

Locations

Barnes-Jewish Hospital, Washington University at St. Louis
RECRUITING

St Louis, Missouri, 63110, United States
Centre of Nephrology, Vilnius University Hospital Santaros Klinikos
RECRUITING

Vilnius, LT-08661, Lithuania
Charite-Medical University of Berlin Department of Nephrology
RECRUITING

Berlin, 10117, Germany
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States
Department of Nephrology and Transplantation Medical University in Bialystok
COMPLETED

Bialystok, 15-540, Poland
Department of Nephrology, The Royal Melbourne Hospital 1 South East
RECRUITING

Melbourne, VIC 3050, Australia
Department of Nephrology, Transplantation and Internal Medicine, University Hospital n.2
RECRUITING

Szczecin, 70-111, Poland
Department of Nephrology, University Medical Centre
RECRUITING

Ljubljana, 21000, Slovenia
Department of Transplantation and General Surgery, Wojewodzki Hospital
RECRUITING

Poznan, 60-479, Poland
Detroit Medical Center, Harper University Hospital of Wayne State University
NOT_YET_RECRUITING

Detroit, Michigan, 48201, United States
Division of Nephrology & UW Organ Transplant Center University of Washington
RECRUITING

Seattle, Washington, 98195, United States
Henry Ford Hospital
RECRUITING

Detroit, Michigan, 48202, United States
Institute for Clinical and Experimental Medicine (IKEM)
RECRUITING

Prague, 140 21 Praha 4, Czechia
Intermountain Transplant Services
RECRUITING

Murray, Utah, 84107, United States
Medical University of Gdańsk Klinika Nefrologii Transplantologii i Chorób Wewnętrznych
RECRUITING

Gdansk, 80-259, Poland
Medical University of Silesia
RECRUITING

Katowice, 40-027, Poland
Medical University of Warsaw, Department of Transplantation Medicine, Nephrology and Internal Diseases
RECRUITING

Warsaw, 02-006, Poland
Pomeranian Medical University, Samodzielny Publiczny Woj. Szpital Zespolony, Oddzial Nefrologii i Transplantacji Nerek
RECRUITING

Szczecin, 71-455, Poland
ST. Paul's Hospital, 6A Providence Building, 1081 Burrard Street
RECRUITING

Vancouver, British Columbia, V6Z 1Y6, Canada
Tampa General Hospital
RECRUITING

Tampa, Florida, 33606, United States
The Children's Memorial Health Institute, Department of Nephrology, Kidney Transplantation and Hypertension
COMPLETED

Warsaw, 04-730, Poland
The Johns Hopkins University, School of Medicine
RECRUITING

Baltimore, Maryland, 21205, United States
Transplant Medicine & Nephrology Clinic, Medical University of Warsaw
RECRUITING

Warsaw, 02-006, Poland
University Hospital Merkur Renal Division
RECRUITING

Zagreb, 1910000, Croatia
University Hospital Zurich
COMPLETED

Zurich, 8091, Switzerland
University Hospital nr1 Bydgoszcz, Klinika Transplantologii
COMPLETED

Bydgoszcz, 85-094, Poland
University Hospitals Cleveland Medical Ctr.
RECRUITING

Cleveland, Ohio, 44106-5048, United States
University of Alberta, Department of Medicine
RECRUITING

Edmonton, Alberta, T6G 2G3, Canada
University of Maryland School of Medicine
RECRUITING

Baltimore, Maryland, 21201, United States
Virginia Commonwealth University Medical Center
RECRUITING

Richmond, Virginia, 23298, United States
Wroclaw Medical University, Department of Nephrology and Transplantation Medicine
RECRUITING

Wroclaw, 50-556, Poland

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