Kidney tissue study aims to unlock secrets of diabetic kidney disease

NCT ID NCT02986984

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is collecting kidney tissue, blood, urine, and genetic samples from 400 adults with diabetes who are already scheduled for a kidney biopsy. Researchers will compare people whose kidney function declines quickly versus slowly to find molecular clues. The goal is to better understand diabetic kidney disease and identify potential targets for future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could reveal new targets for future treatments to slow kidney disease in diabetes.
What could go wrong
This is an observational study, not testing a treatment. It may not directly lead to new therapies, and results depend on careful analysis of complex data.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Albert Einstein College of Medicine

    ACTIVE_NOT_RECRUITING

    The Bronx, New York, 10461, United States

  • Columbia University

    ACTIVE_NOT_RECRUITING

    New York, New York, 10032, United States

  • Lehigh Valley Health Network

    RECRUITING

    Allentown, Pennsylvania, 18103, United States

  • Mount Sinai Hospital

    RECRUITING

    New York, New York, 10029, United States

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

  • Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

  • Oregon Health & Science University

    RECRUITING

    Portland, Oregon, 97239, United States

  • Stanford University

    RECRUITING

    Palo Alto, California, United States

  • University of Arkansas for Medical Sciences

    RECRUITING

    Little Rock, Arkansas, 72205, United States

  • University of Michigan

    ACTIVE_NOT_RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • University of New Mexico

    RECRUITING

    Albuquerque, New Mexico, 87131, United States

  • University of North Carolina

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • University of Southern California

    ACTIVE_NOT_RECRUITING

    Los Angeles, California, 90033, United States

  • University of Texas Health Science Center at San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

  • University of Virginia

    RECRUITING

    Charlottesville, Virginia, 22908, United States

  • Yale University

    RECRUITING

    New Haven, Connecticut, 06510, United States

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