Can a common drug be tailored to help teens lose weight?
NCT ID NCT04986631
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how the drug topiramate works in teenagers with severe obesity. Researchers wanted to understand why some teens lose weight while others don't, by measuring drug levels in the blood. The goal is to eventually personalize dosing for better results.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- topiramate
- What this could lead to
- If successful, this could help doctors tailor topiramate doses for individual teens, making weight loss treatment more effective.
- What could go wrong
- This is an early-phase study with only 62 participants, so results may not apply to all teens. Topiramate can cause side effects like dizziness or tingling.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Minnesota
Minneapolis, Minnesota, 55455, United States
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