New cream shows promise for rare skin condition

NCT ID NCT03972592

Completed Disease control Sponsor: University Hospital, Tours Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a cream containing sirolimus on rare skin growths called microcystic lymphatic malformations, which can ooze, bleed, and cause pain. 55 children and adults applied the cream to one area and a placebo cream to another for 12 weeks. The goal was to see if the sirolimus cream improves the appearance and symptoms better than the placebo.

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Conditions

The condition(s) this trial relates to.

Lymphatic Abnormalities lymphatic malformation microcystic lymphatic malformation vascular malformation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LYMPHATIC MALFORMATION VASCULAR MALFORMATIONS

Contacts and locations

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Locations

ANGERS

Angers, France
BORDEAUX

Bordeaux, France
CAEN

Caen, France
DIJON

Dijon, France
LYON AD

Bron, France
LYON PED

Bron, France
Lariboisiere

Paris, France
Marseille

Marseille, France
Montpellier

Montpellier, France
NANCY

Vandœuvre-lès-Nancy, France
NANTES

Nantes, France
NECKER

Paris, France
NICE

Nice, France
QUIMPER

Quimper, France
RENNES

Rennes, France
TOULOUSE

Toulouse, France
TOURS

Tours, France