LYMPHATIC MALFORMATION
Clinical trials for LYMPHATIC MALFORMATION explained in plain language.
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Glow-in-the-Dark dye could make Children's tumor surgery safer and more effective
Disease control Recruiting nowThis study tests whether using a special dye (indocyanine green) that glows under a special light can help surgeons better see and remove cystic lymphatic malformations in children. About 110 children will be randomly assigned to receive either the dye-guided surgery or standard …
Matched conditions: LYMPHATIC MALFORMATION
Phase: NA • Sponsor: Nanjing Children's Hospital • Aim: Disease control
Last updated May 17, 2026 01:16 UTC
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Weekly drug could tame painful birthmarks with fewer side effects
Disease control Recruiting nowThis study tests whether taking sirolimus once a week can safely shrink abnormal blood or lymph vessel growths (malformations) in children and adults. Current daily dosing causes many side effects, so researchers hope weekly dosing works just as well with fewer problems. Particip…
Matched conditions: LYMPHATIC MALFORMATION
Phase: PHASE2 • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New injection could shrink painful cysts in kids without surgery
Disease control Recruiting nowThis study tests a medicine called TARA-002 that is injected directly into fluid-filled lumps (lymphatic malformations) in children aged 6 months to 18 years. The goal is to see if it can safely shrink or eliminate these cysts, which can cause pain and breathing problems. Up to 3…
Matched conditions: LYMPHATIC MALFORMATION
Phase: PHASE2 • Sponsor: Protara Therapeutics • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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New hope for rare blood vessel disorders: targeted drugs enter trial
Disease control Recruiting nowThis study tests two targeted drugs for people with abnormal blood vessels (vascular malformations). One drug, alpelisib, is for slow-flow types; the other, mirdametinib, is for fast-flow types. About 50 participants aged 2 and older will take the drug for 48 weeks to see if thei…
Matched conditions: LYMPHATIC MALFORMATION
Phase: PHASE2 • Sponsor: Murdoch Childrens Research Institute • Aim: Disease control
Last updated May 12, 2026 13:41 UTC
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Could a common drug shrink birth defects in kids?
Disease control Recruiting nowThis study tests the drug rapamycin in children with severe lymphatic malformations in the head and neck area that cannot be safely removed with surgery. The goal is to see if taking rapamycin for 6 months can shrink these growths by at least one-fifth and improve symptoms like p…
Matched conditions: LYMPHATIC MALFORMATION
Phase: PHASE2 • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated May 11, 2026 20:39 UTC
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Rare disease mystery: researchers launch global registry to track lymphatic disorders
Knowledge-focused Recruiting nowThis study is creating a registry of up to 1,000 people with rare lymphatic anomalies (such as lymphatic malformation, Gorham-Stout disease, and CLOVES syndrome). Researchers will collect information from medical records and annual questionnaires to learn how these conditions pro…
Matched conditions: LYMPHATIC MALFORMATION
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated May 11, 2026 20:40 UTC