CBD oil for aching knees? new study seeks answers

NCT ID NCT07638189

Not yet recruiting Symptom relief Sponsor: University of Tennessee Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests whether a topical CBD oil can reduce pain in people with knee osteoarthritis. Thirty participants will apply either CBD in castor oil or plain castor oil to their knees twice daily for 30 days, then switch treatments. Researchers will track pain scores and sleep quality to see if CBD offers relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cannabidiol (CBD) dissolved in castor oil
What this could lead to: If it works, this could point toward a new, natural option for managing knee osteoarthritis pain without the side effects of current medicines.
What could go wrong: This is a small pilot study with only 30 people, so results may not apply to everyone. CBD's pain-relieving effects are still unproven, and the placebo effect could be strong.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHITIS

Contacts and locations

Locations

University of Tennessee Health Science Center

Memphis, Tennessee, 38163, United States

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