Can an arthritis drug lift the fog of depression?
NCT ID NCT07493317
First seen Mar 25, 2026 · Last updated Apr 24, 2026 · Updated 1 time
Summary
This study tests whether tocilizumab, a drug that blocks a protein linked to inflammation, can help people with major depression who have lost interest or pleasure in life. About 60 adults with depression and signs of immune activation will receive the drug for 8 weeks. Brain scans and mood surveys will measure changes in reward processing.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Icahn School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 10029, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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