New combo therapy aims to tame advanced melanoma
NCT ID NCT03293784
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tested whether adding a TNF-blocking drug (infliximab or certolizumab) to standard immunotherapy (nivolumab and ipilimumab) is safe for people with advanced melanoma that has spread. The main goal was to find the best dose and check for serious side effects. 33 adults with stage IIIc or IV melanoma took part, and the approach aims to better control the disease rather than cure it.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Institut Claudius Regaud IUCT-ONCOPOLE
Toulouse, 31059, France
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Other studies related to the condition(s) this trial covers.
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