New combo therapy for advanced melanoma shows promise in early trial

NCT ID NCT03293784

First seen Apr 04, 2026 · Last updated Apr 26, 2026 · Updated 4 times

Summary

This early-phase study tested whether adding a TNF-blocking drug (infliximab or certolizumab) to standard immunotherapy (nivolumab and ipilimumab) is safe for people with advanced melanoma. 33 adults with metastatic or unresectable melanoma participated. The main goal was to find the best dose and check for side effects. This is not a cure, but aims to better control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Institut Claudius Regaud IUCT-ONCOPOLE

    Toulouse, 31059, France

Conditions

Explore the condition pages connected to this study.