Zapping the brain to decode social fear

NCT ID NCT06274112

Recruiting now Knowledge-focused Sponsor: Auburn University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study uses transcranial magnetic stimulation (TMS) to explore how the brain controls social motivation in adults who avoid social situations due to depression or social anxiety. Forty participants will undergo MRI scans, computer tasks, and personalized TMS over four visits. The goal is to understand brain circuits involved in social avoidance, not to treat it directly.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcranial magnetic stimulation (TMS)
What this could lead to: If successful, this could point toward a personalized brain stimulation treatment for social avoidance in depression and social anxiety.
What could go wrong: This is a small, early-stage study focused on understanding brain circuits, not testing a treatment. It may not lead to a therapy, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

major depressive disorder social phobia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE DISORDER SOCIAL ANXIETY DISORDER SOCIAL AVOIDANT BEHAVIOR

Contacts and locations

Locations

Auburn University
RECRUITING

Auburn, Alabama, 36849, United States

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