New radioactive drug aims to calm cancer bone pain

NCT ID NCT07197645

Recruiting now Symptom relief Sponsor: Telix Pharmaceuticals (Innovations) Pty Limited Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase study tests a single dose of TLX090-Tx, a radioactive drug, in 33 adults with advanced cancer that has spread to the bones and causes pain. The goal is to find a safe dose and see if it can reduce pain. Participants must have at least one painful bone spot and have tried other treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: TLX090-Tx (153Sm-DOTMP)
What this could lead to: If it works, this could provide a new option to reduce severe bone pain in people with advanced cancer that has spread to the bones.
What could go wrong: This is a very early Phase 1 trial with only 33 people, so it is mainly checking safety and dosing. It may not reduce pain, and there could be side effects like low blood counts.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BONE METASTASES IN SUBJECTS WITH ADVANCED CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

bone cancer metastatic carcinoma in the bone metastatic malignant neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BONE METASTASES IN SUBJECTS WITH ADVANCED CANCER BONE PAIN METASTATIC BONE TUMOR

Contacts and locations

Locations

Biogenix Molecular, LLC, CIRA Health
RECRUITING

Miami, Florida, 33165, United States
Excel Diagnostics and Nuclear Oncology Center
RECRUITING

Houston, Texas, 77042, United States
Houston Metro Urology
RECRUITING

Houston, Texas, 77027, United States
NovaCure
RECRUITING

Miami, Florida, 33176, United States
Oncology Consultants
RECRUITING

Houston, Texas, 77030, United States
University of Texas Medical Branch at Galveston (UTMB)
RECRUITING

Houston, Texas, 77555, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.