New study: shoulder surgery helps older cancer patients move better and hurt less

NCT ID NCT07471022

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Not yet recruiting
Registered, but not yet taking participants.
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Cancelled before anyone took part.

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First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 53 patients with cancer that spread to the upper arm bone, causing pain and limited movement. Researchers compared older and younger patients who had shoulder replacement surgery to see if age affected recovery. The goal was to find out if this surgery is safe and helpful for elderly patients.

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Study facts

What this study's own registry entry says, in plain language.

Participants

53 people

The number who actually took part.

Started

Jan 2013

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This study included adult patients with solitary proximal humeral metastases who underwent proximal humeral hemiarthroplasty at our institution between 2013 and 2021. Both male and female patients were eligible. Patients were divided into two groups based on age (≥65 years and \<65 years) to compare surgical outcomes, functional recovery, complications, and survival. All patients had confirmed metastatic bone tumors, with lesions localized to the proximal humerus and without involvement of the scapula or axillary nerve. Patients with multiple bone metastases or severe comorbidities were excluded.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with a single metastatic lesion in the proximal humerus, confirmed by imaging or biopsy. Presence of pathological fracture or a severe osteolytic lesion at risk of fracture (Mirels score ≥9). Poor response to radiotherapy according to RECIST 1.1 criteria. Persistent severe shoulder pain or significant loss of shoulder function. Estimated life expectancy \>3 months at the time of surgery.. Exclusion Criteria: * Patients with multiple bone metastases involving two or more skeletal sites. Metastatic lesions affecting the scapula, axillary nerve, or brachial plexus. Death during the perioperative period. Presence of three or more significant comorbidities, such as uncontrolled diabetes, severe cardiopulmonary disease, or chronic renal failure. Loss to follow-up within 3 months after surgery.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

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