New shunt procedure could extend life for liver patients

NCT ID NCT06576934

Recruiting now Disease control Sponsor: University Hospital Freiburg Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares early placement of a TIPS (a small tube that reroutes blood flow in the liver) against standard treatments like diuretics and fluid drainage in 134 patients with liver cirrhosis and ascites (fluid buildup). The goal is to see if TIPS improves survival and reduces the need for repeated fluid removal. Participants are adults aged 18-79 with specific severity of ascites and liver function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transjugular intrahepatic portosystemic shunt (TIPS) procedure
What this could lead to: If successful, early TIPS could offer a better way to manage ascites and improve survival in liver cirrhosis patients.
What could go wrong: This is a mid-stage trial with 134 participants, so results may not apply to all patients. TIPS carries risks like infection or shunt blockage.

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Conditions

The condition(s) this trial relates to.

Ascites cirrhosis of liver portal hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASCITES HEPATIC LIVER CIRRHOSIS PORTAL HYPERTENSION

Contacts and locations

Locations

University Medical Center Freiburg
RECRUITING

Freiburg im Breisgau, 79106, Germany

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