Triple-Drug cocktail aims to tackle Hard-to-Treat cancers

NCT ID NCT07681297

First seen Jul 02, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study tests a combination of three drugs—tislelizumab, bevacizumab, and capecitabine—in people with advanced solid tumors. The trial focuses on two challenging groups: those whose cancers have stopped responding to immunotherapy and those with tumors that have spread to the brain or central nervous system. The goal is to find a safe dose and see if the combination can shrink tumors or slow their growth.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
tislelizumab, bevacizumab, and capecitabine
What this could lead to
If successful, this combination could offer a new treatment option for people with advanced solid tumors that have stopped responding to immunotherapy or have spread to the brain.
What could go wrong
This is an early-phase study (Phase 1/2) with a small number of participants, so the benefits are not yet proven. The drug combination may cause significant side effects, and it may not work for everyone.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National University Cancer Institute, Singapore, National University Health System

    Singapore, Singapore

More trials for these conditions

Other studies related to the condition(s) this trial covers.