No-Scar thyroid surgery tested against traditional neck cut

NCT ID NCT07055191

First seen Jan 20, 2026 · Last updated Jun 23, 2026 · Updated 24 times

Summary

This study compares a new surgical technique called TOETVA, which removes the thyroid through the mouth leaving no visible scar, to the standard anterior neck surgery. About 616 adults needing thyroid removal will be randomly assigned to one of the two procedures. The main goal is to see if the new method is as safe as the standard one in terms of early complications like nerve damage or bleeding.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AP-HP - Hôpital Avicennes

    NOT_YET_RECRUITING

    Bobigny, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • AP-HP - Hôpital Cochin

    NOT_YET_RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHRU de Nancy Brabois

    NOT_YET_RECRUITING

    Vandœuvre-lès-Nancy, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Dupuytren

    NOT_YET_RECRUITING

    Limoges, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Lille, Hôpital Huriez

    RECRUITING

    Lille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Nantes - Hôtel Dieu

    NOT_YET_RECRUITING

    Nantes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Poitiers

    NOT_YET_RECRUITING

    Poitiers, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Franco-Britannique

    NOT_YET_RECRUITING

    Levallois-Perret, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Lyon Sud

    NOT_YET_RECRUITING

    Pierre-Bénite, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Polyclinique de la Côte Basque Sud

    NOT_YET_RECRUITING

    Saint-Jean-de-Luz, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Transoral Endoscopic Thyroidectomy by Vestibular Approach (TOETVA) - a surgical procedure

What this could lead to

If successful, this could offer patients a thyroid surgery option with no visible neck scar, potentially improving quality of life and reducing stigma.

What could go wrong

This is an early comparative trial, and the new technique is more complex. It may have similar or higher complication rates, and results may not apply to all patients.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.