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Nerve block may cut opioid need after lung surgery

NCT ID NCT03867695

Symptom relief Sponsor: University Hospital, Strasbourg, France Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This trial tests whether a serratus plane block—a local anesthetic injection near the ribs—can reduce morphine use after video-assisted lung surgery. Sixty adults undergoing lobectomy will receive either ropivacaine or a placebo injection alongside general anesthesia. The goal is to see if this nerve block provides better pain control and lowers opioid-related side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ropivacaine
What this could lead to
If it works, this could offer a better way to manage pain after lung surgery, reducing the need for opioids and their side effects.
What could go wrong
This is a small, early-stage trial, so results may not apply to all patients. The block may not reduce pain enough to change standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Sep 2019

Finished

Oct 2020

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: * All patients undergoing lobectomy VATS * Older \> 18 years * Patients who meet criteria of ASA 1 to 3 class Exclusion criteria: * Patient's refusal to participate in the study * Psychiatric disorder (impossibility to collect the informed consent) * Patient under juridical protection * On going an other study * Non balanced epilepsy * 3 grade auriculo-ventricular heart block without pacing * Severe hepatocellular insufficiency * Anti arrhythmic treatment : class III of the Vaughan William's classification * Pregnant patient or/and breastfeeding * History of opioid abuse * Allergy to local anesthetic drug or opioids

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lobectomy Pain post operative Regional anesthesia Video-assisted thoracoscopic surgery

Contacts and locations

Locations

  • Les Hôpitaux Universitaires de Strasbourg

    Strasbourg, 67091, France

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