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New drug TG02 shows promise in early brain cancer trial

NCT ID NCT03224104

Completed Disease control Sponsor: European Organisation for Research and Treatment of Cancer - EORTC Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tested a new drug called TG02 in 71 patients with aggressive brain cancers (anaplastic astrocytoma or glioblastoma). The goal was to find the safest dose when combined with either radiation or chemotherapy. The study included newly diagnosed elderly patients and those whose cancer had returned. Results help guide future research, but the drug is not yet proven as a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anaplastic astrocytoma astrocytoma (excluding glioblastoma) glioblastoma grade III glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTROCYTOMA, GRADE III GLIOBLASTOMA

Contacts and locations

Locations

  • Assistance Publique - Hopitaux de Marseille - Hôpital de La Timone

    Marseille, 13385, France

  • CHRU de Lille

    Lille, France

  • CHU de Lyon - CHU Lyon - Hopital neurologique Pierre Wertheimer

    Bron, 69677, France

  • Erasmus MC Cancer Institute - location Daniel den Hoed

    Rotterdam, 3015, Netherlands

  • Klinikum Der J.W. Goethe Universitaet-Klinik und Poliklinik fur Neurochirurgie

    Frankfurt, 60528, Germany

  • UniversitaetsSpital Zurich

    Zurich, 8091, Switzerland

  • Universitaetskliniken Regensburg - Universitaetsklinikum Regensburg

    Regensburg, 93053, Germany

  • Universitaetskliniken der Uni Wien - Universitaetsklinikum Wien - AKH uniklinieken

    Vienna, 1090, Austria

  • Universitaetsklinikum Bonn

    Bonn, 53205, Germany

  • Universitaetsklinikum Heidelberg - UniversitaetsKlinikum Heidelberg - Head Hospital

    Heidelberg, 69120, Germany

More trials for these conditions

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