New drug aims to shrink nasal polyps without surgery

NCT ID NCT07520162

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called tezepelumab in 230 Chinese adults with chronic sinusitis and nasal polyps. Participants receive injections every four weeks for six doses. Researchers will measure changes in polyp size and nasal congestion over 24 weeks to see if the treatment helps control the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tezepelumab (also called TEZSPIRE®)

What this could lead to

If successful, this could provide a new treatment option for Chinese adults with nasal polyps, reducing polyp size and easing congestion without surgery.

What could go wrong

This is an early-phase, single-arm study with no placebo group, so results may not prove the drug works better than no treatment. Side effects are possible, and the study is limited to Chinese participants.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    NOT_YET_RECRUITING

    Beijing, 100034, China

  • Research Site

    NOT_YET_RECRUITING

    Beijing, 100191, China

  • Research Site

    RECRUITING

    Beijing, 100730, China

  • Research Site

    RECRUITING

    Cangzhou, 061000, China

  • Research Site

    RECRUITING

    Chengdu, 610021, China

  • Research Site

    NOT_YET_RECRUITING

    Chengdu, 610041, China

  • Research Site

    RECRUITING

    Foshan, 528000, China

  • Research Site

    RECRUITING

    Fuzhou, 350005, China

  • Research Site

    NOT_YET_RECRUITING

    Guiyang, 550044, China

  • Research Site

    NOT_YET_RECRUITING

    Hefei, 230601, China

  • Research Site

    NOT_YET_RECRUITING

    Huaian, 223300, China

  • Research Site

    NOT_YET_RECRUITING

    Lanzhou, 730030, China

  • Research Site

    NOT_YET_RECRUITING

    Shenzhen, 518039, China

  • Research Site

    NOT_YET_RECRUITING

    Shijiazhuang, 50051, China

  • Research Site

    NOT_YET_RECRUITING

    Taiyuan, 030001, China

  • Research Site

    NOT_YET_RECRUITING

    Taizhou, 225300, China

  • Research Site

    NOT_YET_RECRUITING

    Wuhan, 430022, China

  • Research Site

    NOT_YET_RECRUITING

    Wuhu, 241004, China

  • Research Site

    NOT_YET_RECRUITING

    Xi'an, 710004, China

  • Research Site

    NOT_YET_RECRUITING

    Yangzhou, 225000, China

  • Research Site

    RECRUITING

    Zibo, 255036, China