Could testosterone therapy be safe for men with prostate cancer? new trial aims to find out
NCT ID NCT06733350
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether testosterone replacement therapy (TRT) is safe and beneficial for men with low testosterone and early-stage prostate cancer who are on active surveillance. Researchers will track cancer progression, quality of life, and whether men stay on active surveillance. The trial aims to address concerns that TRT might fuel cancer growth.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
testosterone replacement therapy
What this could lead to
If it works, this could show that testosterone therapy is safe for men with low testosterone and early prostate cancer, improving their quality of life without raising cancer risk.
What could go wrong
This is a phase 4 trial, but results may not apply to all patients. There is a long-standing concern that testosterone could make prostate cancer grow, so safety is still being tested.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Roswell Park Cancer Institute
RECRUITINGBuffalo, New York, 14263, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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