Testosterone therapy tested as new pain relief for women on opioids
NCT ID NCT04895306
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether giving testosterone to older women with chronic back pain and low testosterone could improve pain, physical function, and quality of life. 36 women received weekly injections of either testosterone or a placebo for several weeks. The goal was to see if testosterone could be a safe and effective way to manage pain and reduce opioid use.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
testosterone cypionate (a form of testosterone)
What this could lead to
If it works, this could point toward a new way to manage chronic pain in older women and reduce reliance on opioids.
What could go wrong
This is a small, early-phase trial with only 36 participants, so results may not apply widely. Testosterone therapy can have side effects, and the benefit over placebo is uncertain.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States