UK study aims to crack the code of brain tumours with genetic testing

NCT ID NCT04274283

Recruiting now Knowledge-focused Sponsor: University of Birmingham Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This UK study is building a network to rapidly analyze the genetics of brain tumours (gliomas) from 1000 patients. By combining tumour and blood samples, researchers hope to classify each tumour more precisely. The goal is to create a system that can quickly match patients with the right targeted therapies in future trials.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could create a system to quickly identify the exact genetic makeup of brain tumours, making it easier to test and deliver personalized treatments.
What could go wrong: This is a feasibility study focused on building infrastructure, not testing a treatment. It may not directly improve outcomes for participants, and the hoped-for targeted therapy trials may not follow.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLIOMA

Contacts and locations

Locations

Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust
TERMINATED

Cambridge, CB2 0QQ, United Kingdom
Charing Cross Hospital, Imperial College Healthcare NHS Trust
RECRUITING

London, W6 8RF, United Kingdom
Churchill Hospital, Oxford University Hospitals NHS Foundation Trust
RECRUITING

Oxford, OX3 9DU, United Kingdom
Freeman Hospital, The Newcastle upon Tyne Hospitals NHS Foundation Trust
RECRUITING

Newcastle upon Tyne, NE7 7DN, United Kingdom
King's College Hospital, King's College Hospital NHS Foundation Trust
RECRUITING

London, SE5 9RS, United Kingdom
NHS Lothian
ACTIVE_NOT_RECRUITING

Edinburgh, EH4 2XU, United Kingdom
Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust
RECRUITING

Birmingham, B15 2TH, United Kingdom
Queen Elizabeth Unviersity Hospital, NHS Greater Glasgow and Clyde Health Board
ACTIVE_NOT_RECRUITING

Glasgow, G51 4TF, United Kingdom
Queen's Medical Centre, Nottingham University Hospitals NHS Trust
RECRUITING

Nottingham, NG7 2UH, United Kingdom
Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust
RECRUITING

Manchester, M6 8HD, United Kingdom
St James's University Hospital, Leeds Teaching Hospitals NHS Trust
RECRUITING

Leeds, LS9 7TF, United Kingdom
The Christie Hospital, The Christie NHS Foundation Trust
RECRUITING

Manchester, M20 4BX, United Kingdom
The Walton Centre, The Walton Centre NHS Foundation Trust
RECRUITING

Liverpool, L9 7LJ, United Kingdom
Velindre Cancer Centre, Velindre University NHS Trust
RECRUITING

Cardiff, CF14 2TL, United Kingdom

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