Could a common blood pressure drug boost energy in ALS?
NCT ID NCT07224269
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tests whether terazosin, a drug used for high blood pressure, can increase energy levels in people with ALS. Twenty participants will take either terazosin or a placebo for 12 weeks. The goal is to see if the drug is safe and if it raises ATP, a key energy molecule, in the body.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- terazosin
- What this could lead to
- If it works, this could point toward a treatment that helps slow ALS by improving how cells produce energy.
- What could go wrong
- This is a very early pilot study with only 20 people, so it may not show clear benefits. It is designed mainly to check safety, not effectiveness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Iowa Health Care
Iowa City, Iowa, 52242, United States
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