Can online therapy help prevent psychosis in At-Risk youth?

NCT ID NCT05968560

Recruiting now Symptom relief Sponsor: Icahn School of Medicine at Mount Sinai Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether cognitive behavioral therapy (CBT) delivered via telehealth can help young people aged 14 to 25 who are at clinical high risk for psychosis. Participants will receive group, family, or individual CBT sessions online. The goal is to see if this approach is practical and effective at improving social and work functioning, reducing symptoms, and preventing the transition to full psychosis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cognitive behavioral therapy (CBT) delivered via telehealth
What this could lead to: If successful, this could provide an accessible, stigma-reducing way to deliver therapy that helps young people at risk for psychosis improve their daily functioning and social connections.
What could go wrong: This is a small, early feasibility study with only 72 participants, so results may not apply broadly. The therapy may not reduce the risk of developing psychosis or may not be as effective as in-person sessions.

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Conditions

The condition(s) this trial relates to.

psychotic disorder prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CLINICAL HIGH RISK FOR PSYCHOSIS (CHR)

Contacts and locations

Locations

Icahn School of Medicine at Mount Sinai
RECRUITING

New York, New York, 10029, United States

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