Can mindfulness stop psychosis before it starts?

NCT ID NCT06870305

Not yet recruiting Prevention Sponsor: Centre Psychothérapique de Nancy Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a 5-session group mindfulness program can reduce distress and prevent psychosis in 270 young people (ages 18-30) at ultra-high risk. Participants will either receive the mindfulness training plus usual care, or usual care alone. The goal is to see if mindfulness helps ease symptoms and lowers the risk of a first psychotic episode.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Mindfulness-based training for psychosis (MBTP) - a group therapy program
What this could lead to: If it works, this could offer a non-drug way to reduce distress and lower the chance of developing psychosis in young people at high risk.
What could go wrong: This is an early-stage trial with no results yet. The mindfulness program is short (5 sessions over 1 month), and its long-term effects are unknown. It may not prevent psychosis for everyone.

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Conditions

The condition(s) this trial relates to.

Psychotic Disorders psychotic disorder prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CLINICAL HIGH RISK FOR PSYCHOSIS (CHR)

Contacts and locations

Locations

Centre Hospitalier Universitaire (CHU) de Brest

Brest, 29200, France
Centre Psychothérapique de Nancy

Laxou, 54520, France

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