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Could a fasting byproduct be the key to metabolic gains?

NCT ID NCT07840807

Knowledge-focused Sponsor: The Seventh Affiliated Hospital of Sun Yat-sen University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 25, 2026 · Last updated Sep 25, 2026

Summary

Researchers at a Chinese hospital reviewed medical records of 1,149 adults with overweight, obesity, type 2 diabetes, or related metabolic conditions who had undergone a structured Traditional Chinese Medicine fasting therapy. The therapy lasts about nine days and combines severe calorie restriction with herbal formulas. The team checked whether rises in beta-hydroxybutyrate, a ketone the body makes during fasting, matched improvements in weight, waist size, blood pressure, blood sugar, and blood fats. No new tests or treatments were given; the study only analyzed existing data.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Traditional Chinese Medicine fasting therapy, a structured 9-day program combining calorie restriction with herbal formulas
What this could lead to
If a link holds between ketone rise and metabolic improvement, beta-hydroxybutyrate could become a marker doctors use to guide fasting-based treatment for obesity and type 2 diabetes.
What could go wrong
This study only reviews old records, so it cannot prove that fasting causes the improvements or that ketones drive them. Records may be incomplete, and the results may not apply to other fasting programs or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

1,149 people

The number who actually took part.

Started

Aug 2026

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with overweight/obesity or metabolism-related conditions who received structured Traditional Chinese Medicine (TCM) fasting therapy at The Seventh Affiliated Hospital, Sun Yat-sen University (Shenzhen) between \[起始年份\] and \[结束年份\], and whose medical records contain serum beta-hydroxybutyrate (βHB) measurements before and after therapy.

Ages

14 to 72 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female patients aged 18 years or older at the time of receiving TCM fasting therapy. * Diagnosed with overweight/obesity or a metabolism-related condition (e.g., overweight/obesity, metabolic syndrome, type 2 diabetes mellitus, dyslipidemia, or hypertension). * Received a structured Traditional Chinese Medicine (TCM) fasting therapy at The Seventh Affiliated Hospital, Sun Yat-sen University (Shenzhen). * Serum beta-hydroxybutyrate (βHB) levels were measured before and after TCM fasting therapy. * Availability of complete medical records containing baseline and post-therapy data on key metabolic indicators (body weight, BMI, waist circumference, blood pressure, lipid profile, and glycemic indices). Exclusion Criteria: * Patients with incomplete medical records lacking essential baseline or post-therapy metabolic data. * Patients with severe comorbidities that could independently affect metabolic outcomes (e.g., active malignancy, severe hepatic or renal insufficiency, or uncontrolled endocrine disorders other than the conditions being studied). * Patients who received other concurrent interventions that could significantly confound metabolic outcomes during the study period. * Pregnant or lactating women. * Patients whose medical records explicitly indicate refusal of data use for research purposes.

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome hypertensive disorder inherited lipid metabolism disorder metabolic syndrome X Obesity obesity disorder Overweight type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diabete type 2 Metabolic syndrome Obesity & overweight

Contacts and locations

Locations

  • The Seventh Affiliated Hospital, Sun Yat-sen University (Shenzhen)

    Shenzhen, Guangdong, 518107, China

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