New drug combo shows promise for untreated CLL/SLL

NCT ID NCT05718869

First seen Nov 05, 2025 · Last updated May 16, 2026 · Updated 24 times

Summary

This study tests a combination of two drugs, tafasitamab and zanubrutinib, in people newly diagnosed with CLL or SLL. The goal is to see if this combination can kill more cancer cells than either drug alone. About 26 adults will take part, and researchers will measure how many achieve a complete response and track any side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

  • City of Hope at Irvine Lennar

    Irvine, California, 92618, United States

  • University of Miami Sylvester Comprehensive Cancer Center

    Miami, Florida, 33146, United States

Conditions

Explore the condition pages connected to this study.