Nasal polyps trial tests stretching biologic doses

NCT ID NCT07187583

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether people with chronic nasal polyps who are stable on biologic drugs like dupilumab or mepolizumab can safely extend the time between doses from every 4 weeks to every 6 or 8 weeks. The goal is to see if symptom control can be maintained with fewer injections. 135 adults who have been on a steady dose for at least three months will participate.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

biologic drugs (dupilumab or mepolizumab)

What this could lead to

If successful, this could allow patients with chronic nasal polyps to take their medication less often while still controlling symptoms, reducing treatment burden and side effects.

What could go wrong

This is a Phase 4 trial with only 135 participants, so results may not apply to everyone. Some patients might lose disease control with longer dosing intervals, requiring a return to the original schedule.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Otorhinolaryngology, Head and Neck Surgery & Audiology, Copenhagen University, Rigshospitalet

    RECRUITING

    Copenhagen, 2100, Denmark

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Dept of otorhinolaryngology, Aalborg University Hospital

    NOT_YET_RECRUITING

    Aalborg, 9000, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Dept of otorhinolaryngology, Gødstrup Regional Hospital

    NOT_YET_RECRUITING

    Herning, 7400, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Dept of otorhinolaryngology, Lillebaelt Hospital

    NOT_YET_RECRUITING

    Vejle, 7100, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Dept of otorhinolaryngology, Nordsjaellands Hospital

    RECRUITING

    Hillerød, 3400, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Dept of otorhinolaryngology, Odense University Hospital

    NOT_YET_RECRUITING

    Odense, 5000, Denmark

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dept of otorhinolaryngology, Sjællands Universitetshospital

    RECRUITING

    Køge, 4600, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Dept of otorhinolaryngology, head and neck surgery, Aarhus University Hospital

    NOT_YET_RECRUITING

    Aarhus, 8200, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Esbjerg Og Grindsted Sygehus

    NOT_YET_RECRUITING

    Esbjerg, 6700, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact