New combo therapy shows promise for tough head and neck cancers

NCT ID NCT03993353

First seen Feb 17, 2026 · Last updated Jun 13, 2026 · Updated 17 times

Summary

This study tested whether adding tadalafil (a drug for erectile dysfunction) to pembrolizumab (an immunotherapy) could help people with advanced head and neck cancer that had come back or spread. Seven adults with measurable disease took part. The main goals were to check safety and see how long they lived after one year. The approach aims to control the disease, not cure it.

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Contacts and locations

Locations

  • UCSD Moores Cancer Center

    La Jolla, California, 92093, United States

Conditions

Explore the condition pages connected to this study.