Race against time: can quick valve surgery save shock patients?
NCT ID NCT06638268
First seen May 12, 2026 · Last updated Jun 22, 2026 · Updated 5 times
Summary
This study tests whether replacing a narrowed heart valve right away (within 12 hours) helps people with severe aortic stenosis who are in cardiogenic shock, compared to the usual approach of stabilizing them in the ICU first. Thirty participants will be randomly assigned to one of the two strategies. The main goal is to see if immediate treatment increases the number of days they are alive and out of the hospital.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Rigshospitalet Copenhagen University Hospital
RECRUITINGCopenhagen O, 2100, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Transcatheter aortic valve implantation (TAVI) procedure
What this could lead to
If it works, this could show that immediate valve replacement saves more lives than stabilizing patients first in the ICU.
What could go wrong
This is a very small early trial with only 30 participants, so results may not apply to everyone. The procedure itself carries risks like bleeding or stroke.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.