Race against time: can quick valve surgery save shock patients?

NCT ID NCT06638268

Recruiting now Disease control Sponsor: Rigshospitalet, Denmark Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether replacing a narrowed heart valve right away (within 12 hours) helps people with severe aortic stenosis who are in cardiogenic shock, compared to the usual approach of stabilizing them in the ICU first. Thirty participants will be randomly assigned to one of the two strategies. The main goal is to see if immediate treatment increases the number of days they are alive and out of the hospital.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Transcatheter aortic valve implantation (TAVI) procedure
What this could lead to: If it works, this could show that immediate valve replacement saves more lives than stabilizing patients first in the ICU.
What could go wrong: This is a very small early trial with only 30 participants, so results may not apply to everyone. The procedure itself carries risks like bleeding or stroke.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis cardiogenic shock Frailty Shock, Cardiogenic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AORTIC STENOSIS CARDIOGENIC SHOCK

Contacts and locations

Locations

Rigshospitalet Copenhagen University Hospital
RECRUITING

Copenhagen O, 2100, Denmark

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