Experimental immune cell treatment tested against nine deadly cancers

NCT ID NCT04044859

Summary

This early-stage trial is testing the safety of a new treatment called ADP-A2M4CD8, which uses a patient's own modified immune cells to fight cancer. The study will enroll 120 adults with one of nine advanced cancers who have specific genetic markers. Researchers will give the cell therapy alone or combined with established immunotherapy drugs to find the safest dose and see if it shrinks tumors.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Clinica Universitaria de Navarra

    Pío, Pamplona, 31008, Spain

  • Duke University Medical Center, Duke Cancer Institute

    Durham, North Carolina, 27710, United States

  • Froedtert Hospital and the Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Hospital Clinico de Valencia

    Ibanez, Valencia, 46010, Spain

  • Hospital Universitario 12 De Octubre

    Madrid, Avenida de Cordoba S/n, 28041, Spain

  • Hospital Universitario Fundacion Jimenez Diaz

    Madrid, 28040, Spain

  • Hospital Universitario HM Sanchinarro CIOCC

    Madrid, 28050, Spain

  • Hospital Universitario Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital Universitario Virgen del Rocio

    Seville, 41013, Spain

  • M.D. Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Name of Institution: Orlando Health Cancer Institute

    Orlando, Florida, 32806, United States

  • OU Health Stephenson Cancer Center

    Oklahoma City, Oklahoma, 73104, United States

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2M9, Canada

  • Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

  • Washington University - School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.