Scientists use novel PET tracer to peer into brains of progressive MS patients

NCT ID NCT04634994

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to understand how brain connections (synapses) are lost in progressive multiple sclerosis (MS). Researchers will use a new type of PET scan to measure synaptic density in 30 people with progressive MS, relapsing-remitting MS, and healthy volunteers. The goal is to see how these brain changes relate to disability, thinking problems, and blood markers. This is an early-phase observational study, not a treatment trial.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

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