New pill could ease diabetic nerve pain for good
NCT ID NCT06696443
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a drug called suzetrigine (VX-548) for long-term safety and pain relief in people with diabetic peripheral neuropathy. About 455 adults who completed a prior 12-week study will take the drug for up to one year. Researchers will track side effects and changes in pain and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
suzetrigine (also known as VX-548), an oral tablet
What this could lead to
If it works, this could provide a new, long-term pain relief option for people with diabetic nerve pain.
What could go wrong
This is an open-label study with no placebo, so results may be less reliable. Side effects are still being monitored, and the drug may not work for everyone.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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3Sync Research - Miami Lakes
Miami Lakes, Florida, 33014, United States
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AMR Daphne, AL
Daphne, Alabama, 36526, United States
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AMR Fort Myers (The Clinical Study Center)
Fort Myers, Florida, 33912, United States
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AMR Kansas City
Kansas City, Missouri, 64114, United States
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AMR Lexington
Lexington, Kentucky, 40509, United States
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AMR Wichita East, KS (Heartland Research Associates)
Wichita, Kansas, 67207, United States
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AMR-Miami
Coral Gables, Florida, 33134, United States
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Accel Research - Decatur
Decatur, Georgia, 30030, United States
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Accel Research - Deland
DeLand, Florida, 32720, United States
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Accel Research Site - St. Petersburg/Largo
Largo, Florida, 33777, United States
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Accel Research Sites - Maitland
Maitland, Florida, 32751, United States
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Angel City Research, Inc
Los Angeles, California, 90010, United States
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Be Well Clinical Studies - Austin
Round Rock, Texas, 78681, United States
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CNS Healthcare - Jacksonville
Jacksonville, Florida, 32256, United States
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Carolinas Pain Institute - Winston-Salem Office
Winston-Salem, North Carolina, 27103, United States
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Clinical Trials Research
Sacramento, California, 95821, United States
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Clinical Trials of South Carolina - Charleston
Charleston, South Carolina, 29406, United States
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Columbia Presbyterian - The Neurological Institute of New York
New York, New York, 10032, United States
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Conquest Clinical Research - Orlando - Neuro
Orlando, Florida, 32832, United States
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Conquest Clinical Research - Winter Park
Winter Park, Florida, 32789, United States
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Dominion Medical Associates, Inc.
Richmond, Virginia, 23219, United States
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Empire Clinical Research
Pomona, California, 91767, United States
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Eximia Research - Raleigh
Raleigh, North Carolina, 27607, United States
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Feinberg School of Medicine - Anesthesiology
Chicago, Illinois, 60611, United States
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HRI - Hassman Research Institute
Marlton, New Jersey, 08053, United States
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Healthcare Research Network - Flossmoor IL
Tinley Park, Illinois, 604773027, United States
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Healthcare Research Network - Hazelwood MO
Hazelwood, Missouri, 63042, United States
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Kalo Clinical Research - Salt Lake City
Salt Lake City, Utah, 84102, United States
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Long Beach Research Institute
Long Beach, California, 90805, United States
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M3 Wake Research - Charleston
Charleston, South Carolina, 29414, United States
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META Medical Research Institute
Dayton, Ohio, 45432, United States
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Mass General Brigham - Brigham and Women's Hospital - Main Campus
Boston, Massachusetts, 02115, United States
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MedVadis Research Corporation
Waltham, Massachusetts, 02451, United States
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Neuro-Pain Medical Center
Fresno, California, 93710, United States
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Northwest Clinical Research Center (NWCRC)
Bellevue, Washington, 98007, United States
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Pinnacle Research Group, LLC
Anniston, Alabama, 36207, United States
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SCLA Management - Pain Management and Injury Relief
Thousand Oaks, California, 91320, United States
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San Antonio Clinical Trials
San Antonio, Texas, 78240, United States
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Scottsdale Clinical Trials
Scottsdale, Arizona, 85260, United States
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Suburban Research Associates - Media
Media, Pennsylvania, 19063, United States
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Suncoast Clinical Research - New Port Richey
New Port Richey, Florida, 34652, United States
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Suncoast Research Associates - Miami
Doral, Florida, 33172, United States
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Swift Clinical OpCo, Inc
Brooklyn, New York, 11226, United States
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Synexus Clinical Research - Cincinnati
Cincinnati, Ohio, 45236, United States
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Synexus Clinical Research - Evansville
Evansville, Indiana, 47714, United States
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Synexus Clinical Research - New York (DRS)
New York, New York, 10017, United States
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Synexus Clinical Research- Anderson
Anderson, South Carolina, 29621, United States
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Tandem Clinical Research- Covington
Covington, Louisiana, 70433, United States
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Velocity Clinical Research - Albuquerque
Albuquerque, New Mexico, 87107, United States
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Velocity Clinical Research - Baton Rouge
Baton Rouge, Louisiana, 70809, United States
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Velocity Clinical Research - Boise
Meridian, Idaho, 83642, United States
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Velocity Clinical Research - Cleveland
Beachwood, Ohio, 44122, United States
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Velocity Clinical Research - Denver
Englewood, Colorado, 80110, United States
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Velocity Clinical Research - Hallandale Beach
Hallandale, Florida, 33009, United States
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Velocity Clinical Research - Medford
Medford, Oregon, 97504, United States
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Velocity Clinical Research - Norfolk
Norfolk, Nebraska, 68701, United States
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Velocity Clinical Research - Providence
East Greenwich, Rhode Island, 02818, United States
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Velocity Clinical Research - Salt Lake City
West Jordan, Utah, 84088, United States
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Velocity Clinical Research - Spartanburg
Spartanburg, South Carolina, 29303, United States
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Velocity Clinical Research - Syracuse
East Syracuse, New York, 13057, United States
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Velocity Clinical Research - Waco
Waco, Texas, 76710, United States
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Velocity Clinical Research - Washington DC
Washington D.C., District of Columbia, 20016, United States
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Velocity Clinical Research, San Bernardino
San Bernardino, California, 92408, United States
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West Clinical Research
Morehead City, North Carolina, 28557, United States
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Zenos Clinical Research
Dallas, Texas, 75230, United States