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Can cannabis ease diabetic nerve pain? new trial seeks answers

NCT ID NCT06490445

Completed Symptom relief Sponsor: Syqe Medical Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 30, 2026 · Updated 3 times

Summary

This study tests whether inhaling medical cannabis three times a day can safely reduce pain in people with diabetic peripheral neuropathy. 122 adults will receive either a low, medium, or high dose of THC or a placebo using a special inhaler. The main goal is to see if pain scores improve after 15 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Medical cannabis (THC) via Syqe inhaler
What this could lead to
If it works, this could offer a new, inhaled option for managing stubborn nerve pain from diabetes.
What could go wrong
This is a small, early-phase trial. The effect may be modest, and side effects like dizziness or drowsiness are possible. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cannabis dependence diabetes mellitus diabetic neuropathy Respiratory Aspiration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETIC PERIPHERAL NEUROPATHIC PAIN

Contacts and locations

Locations

  • Barzilai Medical center

    Ashkelon, 7830604, Israel

  • Beilinson hospital/ Petach Tikva

    Petah Tikva, 4941492, Israel

  • Berlin, Berlin

    Berlin, State of Berlin, 13187, Germany

  • Berlin, Berlin 4010

    Berlin, State of Berlin, 10629, Germany

  • Bnai Zion Medical Center

    Haifa, 3104802, Israel

  • Centrum Medyczne NEUROMED

    Bydgoszcz, 85-163, Poland

  • Centrum Medyczne Pratia Chojnice

    Chojnice, 89-600, Poland

  • Emeritus Research

    Camberwell, Victoria, 3124, Australia

  • Hadassah Medical Center

    Jerusalem, 91120, Israel

  • Hamburg, Hamburg

    Hamburg, Free and Hanseatic City of Hamburg, 20253, Germany

  • Hannover, Lower Saxony

    Hanover, Lower Saxony, 30449, Germany

  • Heidelberg, Baden-Wuerttemberg

    Heidelberg, Baden-Wurttemberg, 69115, Germany

  • Innovate Clinical Research

    Waitara, New South Wales, 2077, Australia

  • Karlsruhe, Baden-Württemberg

    Karlsruhe, Baden-Wurttemberg, 76137, Germany

  • Katowice, Silesia

    Katowice, Silesian Voivodeship, 40-282, Poland

  • Katowice, Śląsk

    Katowice, Silesian Voivodeship, 40-748, Poland

  • Klinische Forschung Dresden GmbH

    Dresden, 3109601, Germany

  • Klinische Forschung Schwerin GmbH

    Schwerin, 19055, Germany

  • Osrodek Badan Klinicznych Neuro-Medic Clinic

    Katowice, 40-686, Poland

  • Ostrava, Ostrava City

    Ostrava, Ostrava City, 71000, Czechia

  • Plzen, Plzen City

    Pilsen, Plzen City, 30100, Czechia

  • Prague, Praha 12

    Prague, Prague, 12000, Czechia

  • Rambam Medical Center

    Haifa, 3109601, Israel

  • Reinfeld, Schleswig-Holstein

    Reinfeld, Schleswig-Holstein, 23858, Germany

  • Rychnov nad Kneznou, Hradec Kralove

    Rychnov nad Kněžnou, Hradec Kralove, 516 01, Czechia

  • Schwerin, Mecklenburg

    Schwerin, Mecklenburg, 19053, Germany

  • Sheba Medical center Hospital

    Ramat Gan, Tel Aviv, 5262100, Israel

  • Sochaczew, Mazowieckie

    Sochaczew, Masovian Voivodeship, 96-500, Poland

  • Swidnica, Dolnoslaskie

    Swidnica, Lower Silesian Voivodeship, 58-100, Poland

  • The Edith Wolfson Medical Center

    Holon, Tel Aviv, 58100, Israel

  • The Royal Melbourne Hospital

    Parkville, Victoria, 3050, Australia

  • Ulm, Baden-Württemberg

    Ulm, Baden-Wurttemberg, 89073, Germany

  • Warszawa, Mazowieckie

    Warsaw, Masovian Voivodeship, 02-172, Poland

  • Warszawa, Mazowieckie 7010

    Warsaw, Masovian Voivodeship, 02-677, Poland

  • Warszawa, Mazowieckie 7011

    Warsaw, Masovian Voivodeship, 01-018, Poland

  • Western Sydney University NICM Health Research Institute (NICM HRI)

    Westmead, New South Wales, 2145, Australia

  • Westmead Hospital

    Westmead, New South Wales, 2145, Australia

  • Ziv Medical Center

    Safed, 13100, Israel

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