Heart scar on MRI may decide who gets a lifesaving shock device

NCT ID NCT07415642

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether an implantable defibrillator (ICD) can reduce the risk of sudden cardiac death in people with non-ischemic dilated cardiomyopathy, a type of heart muscle disease not caused by blocked arteries. Researchers will use MRI scans to find heart scarring (fibrosis) and then randomly assign those with scarring to either get an ICD or continue standard medication. The goal is to see if the ICD improves survival and helps doctors better predict who is at highest risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Implantable Cardioverter-Defibrillator (ICD)

What this could lead to

If successful, this could show that an ICD saves lives in certain heart muscle disease patients and help doctors better identify who needs one.

What could go wrong

The trial hasn't started yet, and it's possible that ICDs may not reduce overall death risk or that complications from the device outweigh benefits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Death, Sudden, Cardiac dilated cardiomyopathy heart failure sudden arrhythmia death syndrome sudden cardiac arrest

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Radboud University Medical Center

    Nijmegen, Netherlands

    Contact

  • University Medical Center Groningen

    Groningen, Netherlands