Heart scar on MRI may decide who gets a lifesaving shock device
NCT ID NCT07415642
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether an implantable defibrillator (ICD) can reduce the risk of sudden cardiac death in people with non-ischemic dilated cardiomyopathy, a type of heart muscle disease not caused by blocked arteries. Researchers will use MRI scans to find heart scarring (fibrosis) and then randomly assign those with scarring to either get an ICD or continue standard medication. The goal is to see if the ICD improves survival and helps doctors better predict who is at highest risk.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Implantable Cardioverter-Defibrillator (ICD)
- What this could lead to
- If successful, this could show that an ICD saves lives in certain heart muscle disease patients and help doctors better identify who needs one.
- What could go wrong
- The trial hasn't started yet, and it's possible that ICDs may not reduce overall death risk or that complications from the device outweigh benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for NON-ISCHEMIC DILATED CARDIOMYOPATHY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Radboud University Medical Center
Nijmegen, Netherlands
-
University Medical Center Groningen
Groningen, Netherlands
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could infusions of cell 'Packages' repair failing hearts?
- Shock therapy: can a heart device save lives in rare angina?
- Butter and bacon for a stronger heart? new trial puts high-fat diet to the test.
- Tiny heart monitor could uncover why dialysis patients die suddenly
- Heart disease detective: 1,000-Person study hunts for hidden genetic triggers of sudden cardiac death
- AI could prevent sudden cardiac death in young athletes