Heart artery blockage showdown: which approach wins?
NCT ID NCT03667196
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at two methods (antegrade and retrograde) used to open completely blocked heart arteries that have been blocked for a while. Researchers will track 4,000 patients to see which approach is safer and more successful, and why some patients need one method over the other. The goal is to help doctors make better decisions for future patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors choose the best technique for each patient with a chronic total coronary occlusion, improving success rates and reducing complications.
What could go wrong
This is an observational study, not a randomized trial, so results may be influenced by patient selection. It does not test a new drug or device, so direct treatment breakthroughs are unlikely.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Asan Medical Center
RECRUITINGSeoul, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Busan Veterans Hospital, Korea Veterans Health Service
RECRUITINGPusan, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Chung-Ang University Gwangmyeong Hospital
RECRUITINGGwangmyeong, South Korea
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Chungbuk National University Hospital
RECRUITINGCheongju-si, South Korea
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Chungnam National University Hospital
RECRUITINGDaejeon, South Korea
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Chungnam National University Sejong Hospital
RECRUITINGSejong, South Korea
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Dong-A University Hospital
RECRUITINGPusan, South Korea
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Gangneung Asan Hospital
RECRUITINGGangneung, South Korea
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Gangwon National University Hospital
RECRUITINGChuncheon, South Korea
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Gosin University Gospel Hospital
RECRUITINGPusan, South Korea
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Gwangju Veterans Hospital, Korea Veterans Health Service
RECRUITINGGwangju, South Korea
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Gyeongsang National University Changwon Hospital
RECRUITINGChangwon, South Korea
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Hallym University Sacred Heart Hospital
RECRUITINGAnyang, South Korea
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Hanyang University Medical Center
RECRUITINGGuri-si, South Korea
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Inha University Hospital
TERMINATEDIncheon, South Korea
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Inje University Haeundae Paik Hospital
RECRUITINGPusan, South Korea
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Inje University Pusan Paik Hospital
RECRUITINGPusan, South Korea
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Kangbuk Samsung Hospital
TERMINATEDSeoul, South Korea
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Keimyung University Dongsan Medical Center
RECRUITINGDaegu, South Korea
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Myongji Hospital
RECRUITINGGoyang-si, South Korea
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Pusan National University Yangsan Hospital
RECRUITINGYangsan, South Korea
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Samsung Medical Center
RECRUITINGSeoul, South Korea
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Seoul national university Bundang hospital
RECRUITINGGyeonggi-do, South Korea
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SoonChunHyang University Hospital Bucheon
RECRUITINGBucheon-si, South Korea
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The Catholic University of Korea, Eunpyeong
RECRUITINGSeoul, South Korea
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The Catholic University of Korea, Incheon ST. MARY'S Hospital
RECRUITINGIncheon, South Korea
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The Catholic University of Korea, ST. Vincent's Hospital
RECRUITINGDaejeon, South Korea
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The Catholic University of Seoul St. Mary's Hospital
RECRUITINGSeoul, South Korea
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Ulsan University Hospital
RECRUITINGUlsan, South Korea
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Veterans Hospital Service Medical Center
RECRUITINGSeoul, South Korea
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Yeungnam University Medical Center
RECRUITINGDaegu, South Korea
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the Catholic University of Korea, Daejeon St. Mary'S Hospital
RECRUITINGDaejeon, South Korea
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••