Heart artery blockage showdown: which approach wins?

NCT ID NCT03667196

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at two methods (antegrade and retrograde) used to open completely blocked heart arteries that have been blocked for a while. Researchers will track 4,000 patients to see which approach is safer and more successful, and why some patients need one method over the other. The goal is to help doctors make better decisions for future patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors choose the best technique for each patient with a chronic total coronary occlusion, improving success rates and reducing complications.
What could go wrong
This is an observational study, not a randomized trial, so results may be influenced by patient selection. It does not test a new drug or device, so direct treatment breakthroughs are unlikely.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Asan Medical Center

    RECRUITING

    Seoul, South Korea

  • Busan Veterans Hospital, Korea Veterans Health Service

    RECRUITING

    Pusan, South Korea

  • Chung-Ang University Gwangmyeong Hospital

    RECRUITING

    Gwangmyeong, South Korea

  • Chungbuk National University Hospital

    RECRUITING

    Cheongju-si, South Korea

  • Chungnam National University Hospital

    RECRUITING

    Daejeon, South Korea

  • Chungnam National University Sejong Hospital

    RECRUITING

    Sejong, South Korea

  • Dong-A University Hospital

    RECRUITING

    Pusan, South Korea

  • Gangneung Asan Hospital

    RECRUITING

    Gangneung, South Korea

  • Gangwon National University Hospital

    RECRUITING

    Chuncheon, South Korea

  • Gosin University Gospel Hospital

    RECRUITING

    Pusan, South Korea

  • Gwangju Veterans Hospital, Korea Veterans Health Service

    RECRUITING

    Gwangju, South Korea

  • Gyeongsang National University Changwon Hospital

    RECRUITING

    Changwon, South Korea

  • Hallym University Sacred Heart Hospital

    RECRUITING

    Anyang, South Korea

  • Hanyang University Medical Center

    RECRUITING

    Guri-si, South Korea

  • Inha University Hospital

    TERMINATED

    Incheon, South Korea

  • Inje University Haeundae Paik Hospital

    RECRUITING

    Pusan, South Korea

  • Inje University Pusan Paik Hospital

    RECRUITING

    Pusan, South Korea

  • Kangbuk Samsung Hospital

    TERMINATED

    Seoul, South Korea

  • Keimyung University Dongsan Medical Center

    RECRUITING

    Daegu, South Korea

  • Myongji Hospital

    RECRUITING

    Goyang-si, South Korea

  • Pusan National University Yangsan Hospital

    RECRUITING

    Yangsan, South Korea

  • Samsung Medical Center

    RECRUITING

    Seoul, South Korea

  • Seoul national university Bundang hospital

    RECRUITING

    Gyeonggi-do, South Korea

  • SoonChunHyang University Hospital Bucheon

    RECRUITING

    Bucheon-si, South Korea

  • The Catholic University of Korea, Eunpyeong

    RECRUITING

    Seoul, South Korea

  • The Catholic University of Korea, Incheon ST. MARY'S Hospital

    RECRUITING

    Incheon, South Korea

  • The Catholic University of Korea, ST. Vincent's Hospital

    RECRUITING

    Daejeon, South Korea

  • The Catholic University of Seoul St. Mary's Hospital

    RECRUITING

    Seoul, South Korea

  • Ulsan University Hospital

    RECRUITING

    Ulsan, South Korea

  • Veterans Hospital Service Medical Center

    RECRUITING

    Seoul, South Korea

  • Yeungnam University Medical Center

    RECRUITING

    Daegu, South Korea

  • the Catholic University of Korea, Daejeon St. Mary'S Hospital

    RECRUITING

    Daejeon, South Korea

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