Can a single injection quiet nerve pain from a pinched spine?

NCT ID NCT07799155

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 02, 2026 · Last updated Sep 03, 2026 · Updated 1 time

Summary

This trial tests whether a steroid injection near the spine can reduce nerve pain in people with lumbosacral radiculopathy, a condition where a herniated disc presses on a nerve root. Researchers will measure pain using a standard scale before the injection and again at 3 weeks and 3 months. The study includes 40 adults with confirmed nerve compression on MRI who are already scheduled for the procedure. The goal is to see if this common treatment meaningfully eases neuropathic pain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Transforaminal epidural steroid injection, a procedure where a steroid is injected near the affected nerve root in the spine under X-ray guidance
What this could lead to
If it works, this could point toward a reliable way to measure and treat nerve-related pain in people with lower back and leg pain from a pinched nerve.
What could go wrong
This is a small, early study with 40 participants, so results may not apply to everyone. The injection carries risks like infection, bleeding, or nerve damage, and pain may not improve.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2026

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years and older * Patients diagnosed with lumbosacral radiculopathy based on clinical evaluation and lumbar MRI findings * Presence of neuropathic pain symptoms associated with lumbosacral radiculopathy * Patients scheduled to undergo transforaminal epidural steroid injection (TFESI) * Patients able to understand and complete the study questionnaires and scales * Voluntary written informed consent provided Exclusion Criteria: * Previous lumbar spinal surgery * Cauda equina syndrome or progressive neurological deficit * Spinal malignancy, infection, or acute vertebral fracture * Pregnancy or breastfeeding * Coagulation disorders or current anticoagulant therapy contraindicating injection procedures * Known allergy to contrast agents, local anesthetics, or corticosteroids * Severe uncontrolled systemic disease * Cognitive impairment preventing completion of assessment scales * Patients unwilling to participate or unable to attend follow-up visits

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

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  2. The official record

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  3. A doctor treating you

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Contacts and locations

Locations

  • Marmara University Pendik Training and Research Hospital, Department of Physical Medicine and Rehabilitation"

    RECRUITING

    Istanbul, Istanbul, 34854, Turkey (Türkiye)

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