Mind over matter: positive framing may boost pain shot results

NCT ID NCT07498140

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether describing a common pain shot (epidural steroid injection) in a very positive way helps reduce leg pain more than a neutral description. Researchers will compare three groups: positive framing of the shot, neutral framing of the shot, and neutral framing of pain medications. The goal is to see if a patient's expectations can improve real-world pain relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

behavioral intervention (positive or neutral framing of epidural steroid injections)

What this could lead to

If it works, this could show that simply describing a treatment in a positive way improves pain relief, without changing the actual procedure.

What could go wrong

This is an early-stage behavioral study, not a drug trial. The effect may be small or not last long, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Back Pain radiculopathy sciatica

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • First Lviv Medical Union

    NOT_YET_RECRUITING

    Lviv, Ukraine

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Phramongkutklao Military Hospital

    RECRUITING

    Bangkok, Thailand

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Walter Reed National Military Medical Center

    ENROLLING_BY_INVITATION

    Bethesda, Maryland, 20814, United States