Zapping brain tumors without zapping memory: new trial for melanoma patients

NCT ID NCT01644591

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase II trial is testing whether a precise, high-dose radiation treatment called stereotactic radiosurgery can control melanoma that has spread to more than three spots in the brain. The study includes 49 patients and also checks whether this approach helps preserve memory and thinking. The goal is to see if this focused radiation can stop tumors from growing while causing less harm to healthy brain tissue.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

stereotactic radiosurgery (focused radiation)

What this could lead to

If it works, this could offer a way to control multiple brain tumors from melanoma while helping patients keep their memory and thinking skills.

What could go wrong

This is a small, early-phase trial with only 49 participants, so results may not apply to everyone. The treatment may not control all tumors or prevent memory decline.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

brain cancer cutaneous melanoma melanoma metastatic malignant neoplasm in the brain metastatic melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States